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Microglial Phagocytosis of Fibrillar β-Amyloid through a β(1) Integrin-Dependent Mechanism

Microglia are the principle immune effector and phagocytic cells in the CNS. These cells are associated with fibrillar β-amyloid (fAβ)-containing plaques found in the brains of Alzheimer's disease (AD) patients. The plaque-associated microglia undergo a phenotypic conversion into an activated p...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Koenigsknecht, Jessica, Landreth, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730228/
https://ncbi.nlm.nih.gov/pubmed/15525768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2557-04.2004
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