Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation

Alzheimer’s disease (AD) is characterized by a progressive cognitive decline and believed to be driven by the self-aggregation of amyloid-β (Aβ) peptide into oligomers and fibrils that accumulate as senile plaques. It is widely accepted that microglia-mediated inflammation is a significant contribut...

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Dettagli Bibliografici
Pubblicato in:Front Aging Neurosci
Autori principali: Caldeira, Cláudia, Cunha, Carolina, Vaz, Ana R., Falcão, Ana S., Barateiro, Andreia, Seixas, Elsa, Fernandes, Adelaide, Brites, Dora
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583148/
https://ncbi.nlm.nih.gov/pubmed/28912710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00277
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