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Microglia change from a reactive to an age-like phenotype with the time in culture

Age-related neurodegenerative diseases have been associated with chronic neuroinflammation and microglia activation. However, cumulative evidence supports that inflammation only occurs at an early stage once microglia change the endogenous characteristics with aging and switch to irresponsive/senesc...

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Bibliografske podrobnosti
Main Authors: Caldeira, Cláudia, Oliveira, Ana F., Cunha, Carolina, Vaz, Ana R., Falcão, Ana S., Fernandes, Adelaide, Brites, Dora
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040822/
https://ncbi.nlm.nih.gov/pubmed/24917789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00152
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