Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous disease in which glial cells participate in both disease onset and progression. Exosomal transfer of mutant copper-zinc superoxide...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Neurosci
Hlavní autoři: Pinto, Sara, Cunha, Carolina, Barbosa, Marta, Vaz, Ana R., Brites, Dora
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434170/
https://ncbi.nlm.nih.gov/pubmed/28567000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00273
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky