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Microglia change from a reactive to an age-like phenotype with the time in culture

Age-related neurodegenerative diseases have been associated with chronic neuroinflammation and microglia activation. However, cumulative evidence supports that inflammation only occurs at an early stage once microglia change the endogenous characteristics with aging and switch to irresponsive/senesc...

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Autors principals: Caldeira, Cláudia, Oliveira, Ana F., Cunha, Carolina, Vaz, Ana R., Falcão, Ana S., Fernandes, Adelaide, Brites, Dora
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040822/
https://ncbi.nlm.nih.gov/pubmed/24917789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00152
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