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Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease
BACKGROUND: Microglial activation is an important histologic characteristic of the pathology of Alzheimer’s disease (AD). One hypothesis is that amyloid beta (Aβ) peptide serves as a specific stimulus for tyrosine kinase-based microglial activation leading to pro-inflammatory changes that contribute...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2012
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388011/ https://ncbi.nlm.nih.gov/pubmed/22673542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-117 |
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