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Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism

Alzheimer’s disease (AD) has been well characterized by the presence of reactive microglia, often associated with Aβ-plaque deposition. The oligomeric form of Aβ peptide (Aβ(o)) has neurotoxic effects in the presence of microglia and is suggested to potentiate proinflammatory changes in microglia in...

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Bibliografiska uppgifter
Huvudupphovsmän: Dhawan, Gunjan, Floden, Angie M., Combs, Colin K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294077/
https://ncbi.nlm.nih.gov/pubmed/22133278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.10.027
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