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Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism
Alzheimer’s disease (AD) has been well characterized by the presence of reactive microglia, often associated with Aβ-plaque deposition. The oligomeric form of Aβ peptide (Aβ(o)) has neurotoxic effects in the presence of microglia and is suggested to potentiate proinflammatory changes in microglia in...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294077/ https://ncbi.nlm.nih.gov/pubmed/22133278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.10.027 |
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