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Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition
BACKGROUND: Amyloid β (Aβ) peptide is hypothesized to stimulate microglia to acquire their characteristic proinflammatory phenotype in Alzheimer’s disease (AD) brains. The specific mechanisms by which Aβ leads to microglial activation remain an area of interest for identifying attractive molecular t...
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| Publicado no: | J Neuroinflammation |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355356/ https://ncbi.nlm.nih.gov/pubmed/25889879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0255-2 |
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