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Pomegranate Polyphenols and Extract Inhibit Nuclear Factor of Activated T-Cell Activity and Microglial Activation In Vitro and in a Transgenic Mouse Model of Alzheimer Disease(1)(2)(3)

Alzheimer disease (AD) brain is characterized by extracellular plaques of amyloid β (Aβ) peptide with reactive microglia. This study aimed to determine whether a dietary intervention could attenuate microgliosis. Memory was assessed in 12-mo-old male amyloid precursor protein/presenilin 1 (APP/PS1)...

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Detalhes bibliográficos
Main Authors: Rojanathammanee, Lalida, Puig, Kendra L., Combs, Colin K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738232/
https://ncbi.nlm.nih.gov/pubmed/23468550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.112.169516
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