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Expression of mutant alpha-synuclein modulates microglial phenotype in vitro
BACKGROUND: Increased reactive microglia are a histological characteristic of Parkinson's disease (PD) brains, positively correlating with levels of deposited α-synuclein protein. This suggests that microglial-mediated inflammatory events may contribute to disease pathophysiology. Mutations in...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104357/ https://ncbi.nlm.nih.gov/pubmed/21554732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-44 |
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