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Nitrated alpha-synuclein and microglial neuroregulatory activities

Microglial neuroinflammatory responses affect the onset and progression of Parkinson’s disease (PD). We posit that such neuroinflammatory responses are, in part, mediated by microglial interactions with nitrated and aggregated α-synuclein (α-syn) released from Lewy bodies as a consequence of dopamin...

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Hlavní autoři: Reynolds, Ashley D., Kadiu, Irena, Garg, Sanjay K., Glanzer, Jason G., Nordgen, Tara, Ciborowski, Pawel, Banerjee, Ruma, Gendelman, Howard E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430927/
https://ncbi.nlm.nih.gov/pubmed/18202920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-008-9100-z
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