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Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
BACKGROUND: The neuropathology of Parkinson's disease (PD) includes loss of dopaminergic neurons in the substantia nigra, nitrated α-synuclein (N-α-Syn) enriched intraneuronal inclusions or Lewy bodies and neuroinflammation. While the contribution of innate microglial inflammatory activities to...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2147051/ https://ncbi.nlm.nih.gov/pubmed/18167537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001376 |
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