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Glucose Directs Amyloid-beta Into Membrane-Active Oligomers

Oligomeric Amyloid-β 1–42 (Aβ-42) peptides are considered to be the most toxic species connected to the occurrence of Alzheimer’s disease. However, not all aggregation conditions promote oligomer formation in vitro, raising the question whether oligomer formation in vivo also requires a specific sui...

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Bibliographic Details
Published in:Phys Chem Chem Phys
Main Authors: Kedia, Niraja, Almisry, Michael, Bieschke, Jan
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654640/
https://ncbi.nlm.nih.gov/pubmed/28671211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cp02849k
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