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Overcoming resistance to BRAF inhibitors
The discovery of activating mutations in the serine/threonine (S/T) kinase BRAF followed by a wave of follow-up research manifested that the MAPK-pathway plays a critical role in melanoma initiation and progression. BRAF and MEK inhibitors produce an unparalleled response rate in melanoma, but it is...
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| 出版年: | Ann Transl Med |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
AME Publishing Company
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5653517/ https://ncbi.nlm.nih.gov/pubmed/29114545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2017.06.09 |
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