Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A

Myelodysplastic syndromes (MDS) are a diverse group of malignant clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis, dysplastic cell morphology in one or more hematopoietic lineages, and a risk of progression to acute myeloid leukemia (AML). Approximately 50% of MDS...

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Vydáno v:Oncotarget
Hlavní autoři: Oben, Karine Z., Alhakeem, Sara S., McKenna, Mary K., Brandon, Jason A., Mani, Rajeswaran, Noothi, Sunil K., Jinpeng, Liu, Akunuru, Shailaja, Dhar, Sanjit K., Singh, Inder P., Liang, Ying, Wang, Chi, Abdel-Latif, Ahmed, Stills Jr, Harold F., St. Clair, Daret K., Geiger, Hartmut, Muthusamy, Natarajan, Tohyama, Kaoru, Gupta, Ramesh C., Bondada, Subbarao
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652791/
https://ncbi.nlm.nih.gov/pubmed/29100399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20497
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