Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A

Myelodysplastic syndromes (MDS) are a diverse group of malignant clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis, dysplastic cell morphology in one or more hematopoietic lineages, and a risk of progression to acute myeloid leukemia (AML). Approximately 50% of MDS...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Oben, Karine Z., Alhakeem, Sara S., McKenna, Mary K., Brandon, Jason A., Mani, Rajeswaran, Noothi, Sunil K., Jinpeng, Liu, Akunuru, Shailaja, Dhar, Sanjit K., Singh, Inder P., Liang, Ying, Wang, Chi, Abdel-Latif, Ahmed, Stills Jr, Harold F., St. Clair, Daret K., Geiger, Hartmut, Muthusamy, Natarajan, Tohyama, Kaoru, Gupta, Ramesh C., Bondada, Subbarao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652791/
https://ncbi.nlm.nih.gov/pubmed/29100399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20497
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