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Nuclear Factor κB- and Specificity Protein 1-dependent p53-mediated Bi-directional Regulation of the Human Manganese Superoxide Dismutase Gene

Tumor suppressor p53 is known to activate certain sets of genes while suppressing others. However, whether p53 can both activate and suppress the same gene is unclear. To address this question, concentration-dependent p53 effect on the manganese superoxide dismutase (MnSOD) gene was investigated. By...

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Bibliografski detalji
Glavni autori: Dhar, Sanjit K., Xu, Yong, St. Clair, Daret K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843232/
https://ncbi.nlm.nih.gov/pubmed/20061391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060715
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