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4β‐Hydroxycholesterol level significantly correlates with steady‐state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients
AIM: 4β‐Hydroxycholesterol (4βOHC) is sensitive towards induction or inhibition of CYP3A4, but its potential usefulness as a dosing biomarker remains to be demonstrated. The aim of this study was to investigate the correlation between 4βOHC levels and steady‐state concentrations (Css) of quetiapine,...
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| Publié dans: | Br J Clin Pharmacol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5651320/ https://ncbi.nlm.nih.gov/pubmed/28585378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13341 |
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