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The CYP3A biomarker 4β‐hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation

AIMS: Tacrolimus is a cornerstone in modern immunosuppressive therapy after kidney transplantation. Tacrolimus dosing is challenged by considerable pharmacokinetic variability, both between patients and over time after transplantation, partly due to variability in cytochrome P450 3A (CYP3A) activity...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Størset, Elisabet, Hole, Kristine, Midtvedt, Karsten, Bergan, Stein, Molden, Espen, Åsberg, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465334/
https://ncbi.nlm.nih.gov/pubmed/28146606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13248
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