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Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation

Following organ engraftment, initial dosing of tacrolimus is based on recipient weight and adjusted by measured C(0) concentrations. The bioavailability and elimination of tacrolimus are affected by the patients CYP3A5 genotype. Prospective data of the clinical advantage of knowing patient's CY...

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Main Authors:	Åsberg, Anders, Midtvedt, Karsten, van Guilder, Mike, Størset, Elisabet, Bremer, Sara, Bergan, Stein, Jelliffe, Roger, Hartmann, Anders, Neely, Michael N
格式:	Artigo
語言:	Inglês
出版:	BlackWell Publishing Ltd 2013
主題:	Clinical Research
在線閱讀:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3852421/ https://ncbi.nlm.nih.gov/pubmed/24118301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tri.12194
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Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation

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