Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation

Following organ engraftment, initial dosing of tacrolimus is based on recipient weight and adjusted by measured C(0) concentrations. The bioavailability and elimination of tacrolimus are affected by the patients CYP3A5 genotype. Prospective data of the clinical advantage of knowing patient's CY...

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Dades bibliogràfiques
Autors principals: Åsberg, Anders, Midtvedt, Karsten, van Guilder, Mike, Størset, Elisabet, Bremer, Sara, Bergan, Stein, Jelliffe, Roger, Hartmann, Anders, Neely, Michael N
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2013
Matèries:
Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852421/
https://ncbi.nlm.nih.gov/pubmed/24118301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tri.12194
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