Učitavanje...

The CYP3A biomarker 4β‐hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation

AIMS: Tacrolimus is a cornerstone in modern immunosuppressive therapy after kidney transplantation. Tacrolimus dosing is challenged by considerable pharmacokinetic variability, both between patients and over time after transplantation, partly due to variability in cytochrome P450 3A (CYP3A) activity...

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Bibliografski detalji
Izdano u:Br J Clin Pharmacol
Glavni autori: Størset, Elisabet, Hole, Kristine, Midtvedt, Karsten, Bergan, Stein, Molden, Espen, Åsberg, Anders
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465334/
https://ncbi.nlm.nih.gov/pubmed/28146606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13248
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