Wird geladen...

4β‐Hydroxycholesterol level significantly correlates with steady‐state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients

AIM: 4β‐Hydroxycholesterol (4βOHC) is sensitive towards induction or inhibition of CYP3A4, but its potential usefulness as a dosing biomarker remains to be demonstrated. The aim of this study was to investigate the correlation between 4βOHC levels and steady‐state concentrations (Css) of quetiapine,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Gjestad, Caroline, Haslemo, Tore, Andreassen, Ole A., Molden, Espen
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651320/
https://ncbi.nlm.nih.gov/pubmed/28585378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13341
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!