MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy

Synucleinopathies, neurodegenerative disorders with alpha-synuclein (α-syn) accumulation, are the second leading cause of neurodegeneration in the elderly, however no effective disease-modifying alternatives exist for these diseases. Multiple system atrophy (MSA) is a fatal synucleinopathy character...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Valera, Elvira, Spencer, Brian, Mott, Jennifer, Trejo, Margarita, Adame, Anthony, Mante, Michael, Rockenstein, Edward, Troncoso, Juan C., Beach, Thomas G., Masliah, Eliezer, Desplats, Paula
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650998/
https://ncbi.nlm.nih.gov/pubmed/29089869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00329
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