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Glutaminase C overexpression in the brain induces learning deficits, synaptic dysfunctions, and neuroinflammation in mice

Glutaminolysis, a metabolic process that converts glutamine to glutamate, is particularly important for the central nervous system since glutamate is the major transmitter of excitatory synapses. Glutaminase is the mitochondrial enzyme that catalyzes the first step of glutaminolysis. Two genes encod...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Wang, Yi, Li, Yuju, Zhao, Runze, Wu, Beiqing, Lanoha, Blaise, Tong, Zenghan, Peer, Justin, Liu, Jianhui, Xiong, Huangui, Huang, Yunlong, Zheng, Jialin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650935/
https://ncbi.nlm.nih.gov/pubmed/28624534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.06.007
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