Propofol Reduces Microglia Activation and Neurotoxicity Through Inhibition of Extracellular Vesicle Release

Propofol is an established anesthetic widely used for induction and maintenance of anesthesia. We investigated propofol for its anti-inflammatory effects on microglia and found that propofol treatment is associated with substantial lower levels of extracellular vesicles (EVs) in immune activated mic...

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Détails bibliographiques
Publié dans:J Neuroimmunol
Auteurs principaux: Liu, Jianhui, Li, Yuju, Xia, Xiaohuan, Yang, Xiaoyu, Zhao, Runze, Peer, Justin, Wang, Hongyun, Tong, Zenghan, Gao, Fengtong, Lin, Hai, Wu, Beiqing, Huang, Yunlong, Zheng, Jialin
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571156/
https://ncbi.nlm.nih.gov/pubmed/31108401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2019.05.003
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