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Glutaminase C overexpression in the brain induces learning deficits, synaptic dysfunctions, and neuroinflammation in mice

Glutaminolysis, a metabolic process that converts glutamine to glutamate, is particularly important for the central nervous system since glutamate is the major transmitter of excitatory synapses. Glutaminase is the mitochondrial enzyme that catalyzes the first step of glutaminolysis. Two genes encod...

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Bibliografiske detaljer
Udgivet i:Brain Behav Immun
Main Authors: Wang, Yi, Li, Yuju, Zhao, Runze, Wu, Beiqing, Lanoha, Blaise, Tong, Zenghan, Peer, Justin, Liu, Jianhui, Xiong, Huangui, Huang, Yunlong, Zheng, Jialin
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650935/
https://ncbi.nlm.nih.gov/pubmed/28624534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.06.007
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