Glutaminase C overexpression in the brain induces learning deficits, synaptic dysfunctions, and neuroinflammation in mice

Glutaminolysis, a metabolic process that converts glutamine to glutamate, is particularly important for the central nervous system since glutamate is the major transmitter of excitatory synapses. Glutaminase is the mitochondrial enzyme that catalyzes the first step of glutaminolysis. Two genes encod...

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Vydáno v:Brain Behav Immun
Hlavní autoři: Wang, Yi, Li, Yuju, Zhao, Runze, Wu, Beiqing, Lanoha, Blaise, Tong, Zenghan, Peer, Justin, Liu, Jianhui, Xiong, Huangui, Huang, Yunlong, Zheng, Jialin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650935/
https://ncbi.nlm.nih.gov/pubmed/28624534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.06.007
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