Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments

Experimental cerebral malaria (ECM) is a gamma interferon (IFN-γ)-dependent syndrome. However, whether IFN-γ promotes ECM through direct and synergistic targeting of multiple cell populations or by acting primarily on a specific responsive cell type is currently unknown. Here, using a panel of cell-...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Villegas-Mendez, Ana, Strangward, Patrick, Shaw, Tovah N., Rajkovic, Ivana, Tosevski, Vinko, Forman, Ruth, Muller, Werner, Couper, Kevin N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649021/
https://ncbi.nlm.nih.gov/pubmed/28874445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01035-16
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