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Long-Lived CD4(+)IFN-γ(+) T Cells rather than Short-Lived CD4(+)IFN-γ(+)IL-10(+) T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection

CD4(+) T cells that produce IFN-γ are the source of host-protective IL-10 during primary infection with a number of different pathogens, including Plasmodium spp. The fate of these CD4(+)IFN-γ(+)IL-10(+) T cells following clearance of primary infection and their subsequent influence on the course of...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Villegas-Mendez, Ana, Inkson, Colette A., Shaw, Tovah N., Strangward, Patrick, Couper, Kevin N.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055201/
https://ncbi.nlm.nih.gov/pubmed/27630165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600968
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