Parasite-Specific CD4(+) IFN-γ(+) IL-10(+) T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 and ICOS during Blood-Stage Malaria Infection

Immune-mediated pathology in interleukin-10 (IL-10)-deficient mice during blood-stage malaria infection typically manifests in nonlymphoid organs, such as the liver and lung. Thus, it is critical to define the cellular sources of IL-10 in these sensitive nonlymphoid compartments during infection. Mo...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Villegas-Mendez, Ana, Shaw, Tovah N., Inkson, Colette A., Strangward, Patrick, de Souza, J. Brian, Couper, Kevin N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693994/
https://ncbi.nlm.nih.gov/pubmed/26459508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01100-15
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