Macrophage-Mediated but Gamma Interferon-Independent Innate Immune Responses Control the Primary Wave of Plasmodium yoelii Parasitemia

In most models of blood-stage malaria infection, proinflammatory immune responses are required for control of infection and elimination of parasites. We hypothesized therefore that the fulminant infections caused in mice by the lethal strain of Plasmodium yoelii (17XL) might be due to failure to act...

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Detalhes bibliográficos
Main Authors: Couper, Kevin N., Blount, Daniel G., Hafalla, Julius C. R., van Rooijen, Nico, de Souza, J. Brian, Riley, Eleanor M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168355/
https://ncbi.nlm.nih.gov/pubmed/17923512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-07
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