Macrophage-Mediated but Gamma Interferon-Independent Innate Immune Responses Control the Primary Wave of Plasmodium yoelii Parasitemia

In most models of blood-stage malaria infection, proinflammatory immune responses are required for control of infection and elimination of parasites. We hypothesized therefore that the fulminant infections caused in mice by the lethal strain of Plasmodium yoelii (17XL) might be due to failure to act...

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Détails bibliographiques
Auteurs principaux: Couper, Kevin N., Blount, Daniel G., Hafalla, Julius C. R., van Rooijen, Nico, de Souza, J. Brian, Riley, Eleanor M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2007
Sujets:
Fungal and Parasitic Infections
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168355/
https://ncbi.nlm.nih.gov/pubmed/17923512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-07
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