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Macrophage-Mediated but Gamma Interferon-Independent Innate Immune Responses Control the Primary Wave of Plasmodium yoelii Parasitemia

In most models of blood-stage malaria infection, proinflammatory immune responses are required for control of infection and elimination of parasites. We hypothesized therefore that the fulminant infections caused in mice by the lethal strain of Plasmodium yoelii (17XL) might be due to failure to act...

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Autors principals: Couper, Kevin N., Blount, Daniel G., Hafalla, Julius C. R., van Rooijen, Nico, de Souza, J. Brian, Riley, Eleanor M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168355/
https://ncbi.nlm.nih.gov/pubmed/17923512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-07
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