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Cardiac Reprogramming Factor Gata4 Reduces Post-Infarct Cardiac Fibrosis through Direct Repression of the Pro-Fibrotic Mediator Snail

OBJECTIVE: The administration of a variety of reprogramming factor cocktails has now been shown to reprogram cardiac fibroblasts into induced cardiomyocyte-like cells (iCMs). Reductions in ventricular fibrosis observed after reprogramming factor administration, however, seem to far exceed the extent...

詳細記述

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書誌詳細
出版年:J Thorac Cardiovasc Surg
主要な著者: Mathison, Megumi, Singh, Vivek P., Sanagasetti, Deepthi, Yang, Lina, Pinnamaneni, Jaya Pratap, Yang, Jianchang, Rosengart, Todd K.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647235/
https://ncbi.nlm.nih.gov/pubmed/28711329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2017.06.035
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