Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani

Widespread resistance towards antimony and reports of relapses following miltefosine treatment has severely affected the management of visceral leishmaniasis (VL) in the Indian subcontinent. Paromomycin (PMM), an aminoglycoside antibiotic, has been licensed for VL treatment in India in 2007. Althoug...

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Udgivet i:Int J Parasitol Drugs Drug Resist
Main Authors: Verma, Aditya, Bhandari, Vasundhra, Deep, Deepak Kumar, Sundar, Shyam, Dujardin, Jean Claude, Singh, Ruchi, Salotra, Poonam
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645162/
https://ncbi.nlm.nih.gov/pubmed/29035735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.10.004
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