Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani

Widespread resistance towards antimony and reports of relapses following miltefosine treatment has severely affected the management of visceral leishmaniasis (VL) in the Indian subcontinent. Paromomycin (PMM), an aminoglycoside antibiotic, has been licensed for VL treatment in India in 2007. Althoug...

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Vydáno v:Int J Parasitol Drugs Drug Resist
Hlavní autoři: Verma, Aditya, Bhandari, Vasundhra, Deep, Deepak Kumar, Sundar, Shyam, Dujardin, Jean Claude, Singh, Ruchi, Salotra, Poonam
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645162/
https://ncbi.nlm.nih.gov/pubmed/29035735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.10.004
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