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Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani

Widespread resistance towards antimony and reports of relapses following miltefosine treatment has severely affected the management of visceral leishmaniasis (VL) in the Indian subcontinent. Paromomycin (PMM), an aminoglycoside antibiotic, has been licensed for VL treatment in India in 2007. Althoug...

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Bibliografski detalji
Izdano u:Int J Parasitol Drugs Drug Resist
Glavni autori: Verma, Aditya, Bhandari, Vasundhra, Deep, Deepak Kumar, Sundar, Shyam, Dujardin, Jean Claude, Singh, Ruchi, Salotra, Poonam
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645162/
https://ncbi.nlm.nih.gov/pubmed/29035735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.10.004
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