Experimental Induction of Paromomycin Resistance in Antimony-Resistant Strains of L. donovani: Outcome Dependent on In Vitro Selection Protocol

Paromomycin (PMM) has recently been introduced for treatment of visceral leishmaniasis in India. Although no clinical resistance has yet been reported, proactive vigilance should be warranted. The present in vitro study compared the outcome and stability of experimental PMM-resistance induction on p...

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Main Authors: Hendrickx, Sarah, Inocêncio da Luz, Raquel Andrea, Bhandari, Vasundhra, Kuypers, Kristel, Shaw, Craig D., Lonchamp, Julien, Salotra, Poonam, Carter, Katharine, Sundar, Shyam, Rijal, Suman, Dujardin, Jean-Claude, Cos, Paul, Maes, Louis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362622/
https://ncbi.nlm.nih.gov/pubmed/22666513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001664
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