The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis

ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date. Caenorhabditis elegans lacking ADARs exhibit reduced chemotaxis, but the targets...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:eLife
Main Authors: Deffit, Sarah N, Yee, Brian A, Manning, Aidan C, Rajendren, Suba, Vadlamani, Pranathi, Wheeler, Emily C, Domissy, Alain, Washburn, Michael C, Yeo, Gene W, Hundley, Heather A
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Assuntos:
Chromosomes and Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644944/
https://ncbi.nlm.nih.gov/pubmed/28925356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28625
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares