The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis

ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date. Caenorhabditis elegans lacking ADARs exhibit reduced chemotaxis, but the targets...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Deffit, Sarah N, Yee, Brian A, Manning, Aidan C, Rajendren, Suba, Vadlamani, Pranathi, Wheeler, Emily C, Domissy, Alain, Washburn, Michael C, Yeo, Gene W, Hundley, Heather A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2017
Onderwerpen:
Chromosomes and Gene Expression
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644944/
https://ncbi.nlm.nih.gov/pubmed/28925356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28625
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