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Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development

Adenosine (A) to inosine (I) RNA editing contributes to transcript diversity and modulates gene expression in a dynamic, cell type–specific manner. During mammalian brain development, editing of specific adenosines increases, whereas the expression of A-to-I editing enzymes remains unchanged, sugges...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genome Res
Hauptverfasser: Rajendren, Suba, Dhakal, Alfa, Vadlamani, Pranathi, Townsend, Jack, Deffit, Sarah N., Hundley, Heather A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849389/
https://ncbi.nlm.nih.gov/pubmed/33355311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.267575.120
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