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The dsRBP and inactive editor, ADR-1, utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptome
Inadequate adenosine-to-inosine editing of noncoding regions occurs in disease, often uncorrelated with ADAR levels, underscoring the need to study deaminase-independent control of editing. C. elegans have two ADAR proteins, ADR-2 and the theoretically catalytically inactive ADR-1. Using high-throug...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959997/ https://ncbi.nlm.nih.gov/pubmed/24508457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.01.011 |
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