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De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures

The folding of natural proteins typically relies on hydrophobic packing, metal binding, or disulfide bond formation in the protein core. Alternatively, a 3D structure can be defined by incorporating a multivalent cross-linking agent, and this approach has been successfully developed for the selectio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Dang, Bobo, Wu, Haifan, Mulligan, Vikram Khipple, Mravic, Marco, Wu, Yibing, Lemmin, Thomas, Ford, Alexander, Silva, Daniel-Adriano, Baker, David, DeGrado, William F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642715/
https://ncbi.nlm.nih.gov/pubmed/28973862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710695114
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