SNAC-tag for Sequence-specific Chemical Protein Cleavage

Biocompatible chemical protein cleavage methods have been long-sought to replace enzymatic cleavages, but have yet to be realized. Here, we report the development of the SNAC-tag (Sequence-specific Nickel Assisted Cleavage) to achieve sequence-specific chemical protein cleavage under biocompatible c...

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Publicado en:Nat Methods
Main Authors: Dang, Bobo, Mravic, Marco, Hu, Hailin, Schmidt, Nathan, Mensa, Bruk, DeGrado, William F.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443254/
https://ncbi.nlm.nih.gov/pubmed/30923372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0357-3
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