Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis

Lignende værker

• Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors
  af: Ratnayake, Wishrawana S., et al.
  Udgivet: (2018)
• Effects of Atypical Protein Kinase C Inhibitor (DNDA) on Lung Cancer Proliferation and Migration by PKC-ι/FAK Ubiquitination Through the Cbl-b Pathway
  af: BommaReddy, Raja Reddy, et al.
  Udgivet: (2020)
• Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion
  af: Ratnayake, Wishrawana S., et al.
  Udgivet: (2021)
• Inhibition of atypical protein kinase C-ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade
  af: Apostolatos, André H., et al.
  Udgivet: (2018)
• Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypes
  af: Smalley, Tracess, et al.
  Udgivet: (2019)