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Catalytic Enantioselective Carbonyl Allylation and Propargylation via Alcohol Mediated Hydrogen Transfer: Merging the Chemistry of Grignard and Sabatier

Merging the characteristics of transfer hydrogenation and carbonyl addition, we have developed a new class of catalytic enantioselective C-C bond formations. In these processes, hydrogen transfer between alcohols and π-unsaturated reactants generates carbonyl-organometal pairs that combine to delive...

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Detalhes bibliográficos
Publicado no:Acc Chem Res
Main Authors: Kim, Seung Wook, Zhang, Wandi, Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641472/
https://ncbi.nlm.nih.gov/pubmed/28792731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.7b00308
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