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Catalytic Enantioselective Synthesis of Chiral Organofluorine Compounds: Alcohol-Mediated Hydrogen Transfer for Catalytic Carbonyl Reductive Coupling

Alcohol-mediated carbonyl addition has enabled catalytic enantioselective syntheses of diverse fluorine-containing compounds without the need for stoichiometric metals or discrete redox manipulations. Reactions of this type may be separated into two broad categories: redox-neutral hydrogen auto-tran...

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Detalhes bibliográficos
Publicado no:Org Process Res Dev
Main Authors: Tauber, Johannes, Schwartz, Leyah A., Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516892/
https://ncbi.nlm.nih.gov/pubmed/32982140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.oprd.9b00035
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