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Enantioselective Total Synthesis of Andrographolide and 14-Hydroxy-Colladonin: Carbonyl Reductive Coupling and trans-Decalin Formation via Hydrogen Transfer
[Image: see text] King of Bitters. An enantioselective total synthesis of the labdane diterpenoid andrographolide, the bitter principle of the medicinal herb Andrographis paniculata (known as “King of Bitters”), is accomplished in 14 steps (LLS) - 10 steps shorter than the prior total synthesis. Key...
Tallennettuna:
| Julkaisussa: | Angew Chem Int Ed Engl |
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| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7920188/ https://ncbi.nlm.nih.gov/pubmed/32896046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202011363 |
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