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HIV-1 Resistance to Dolutegravir Is Affected by Cellular Histone Acetyltransferase Activity
Integrase strand transfer inhibitors (INSTIs) are the newest class of antiretrovirals to be approved for the treatment of HIV infection. Canonical resistance to these competitive inhibitors develops through substitutions in the integrase active site that disrupt drug-protein interactions. However, r...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640858/ https://ncbi.nlm.nih.gov/pubmed/28835492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00912-17 |
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