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HIV drug resistance against strand transfer integrase inhibitors

Integrase strand transfer inhibitors (INSTIs) are the newest class of antiretroviral drugs to be approved for treatment and act by inhibiting the essential HIV protein integrase from inserting the viral DNA genome into the host cell’s chromatin. Three drugs of this class are currently approved for u...

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Publicat a:Retrovirology
Autors principals: Anstett, Kaitlin, Brenner, Bluma, Mesplede, Thibault, Wainberg, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460515/
https://ncbi.nlm.nih.gov/pubmed/28583191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0360-7
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